Dermal & Cosmetic Research

Argireline

Acetyl hexapeptide-8

Also known as Acetyl hexapeptide-8, Acetyl hexapeptide-3.

Acetyl hexapeptide-8, a SNAP-25 fragment investigated for inhibition of SNARE-complex formation in cell culture and reconstituted-vesicle models.

Current lot: SN-ARG-2607
Purity: 99.12% by HPLC
Tested: Jul 2, 2026
Stocked in: United States, Canada, Australia

Synamino Sciences research vial with a silver cap on a teal background

Ships from

Vial size

$30.00

USD · 10 mg · In stock

Qty

Order by 2:00 PM PT for same-day dispatch from Reno, Nevada. 1–3 business days by USPS Priority and UPS. Free shipping over $150.00.

For laboratory research use only. Not for human or veterinary use.

About the compound

Argireline is the trade-style name for acetyl hexapeptide-8 (historically acetyl hexapeptide-3), a six-residue peptide patterned on the N-terminus of SNAP-25. Its research use centres on vesicle-fusion assays and cosmetic-science formulation studies.

Supplied as a lyophilized powder for reconstitution.

Studied inVesicle fusion · SNARE complex · Formulation science

Certificate of analysis

The certificate for the lot currently shipping. Every vial in that lot carries the same lot number on its label.

Certificate of analysis

Argireline · 10 mg

Lot SN-ARG-2607 · tested Jul 2, 2026

99.12%

Purity by HPLC

Labeled: 10 mg
Measured: 10.1 mg
Panel: 6 passed · 2 reported
Laboratory: Independent ISO/IEC 17025 accredited laboratory

Assay	Method	Result	Outcome
Appearance	Visual	White lyophilized powder	Pass
Purity	HPLC · spec ≥ 98%	99.12%	Pass
Net peptide content	HPLC	10.1 mg	Reported
Identity	LC-MS	Confirmed	Pass
Heavy metals	ICP-MS	Not detected	Pass
Sterility	USP <71>	No growth	Pass
Endotoxin	LAL · USP <85>	< 0.05 EU/mL	Reported
Residual solvents	GC-HS	Within limits	Pass

Specification and storage

CAS number: 616204-22-9
Molecular formula: C34H60N14O12S
Molecular weight: 889.0 g/mol
Residues: 6
Sequence: Ac-EEMQRR-NH2
Reference record: PubChem entry

Storage

Sealed lyophilized vials are stable at room temperature for short periods; store at 2–8 °C for routine use.
For long-term storage keep sealed vials at −20 °C, protected from light and moisture.
Reconstituted solutions should be refrigerated at 2–8 °C and used within the period defined by your laboratory's protocol.

Literature

Peer-reviewed publications on this compound. Provided for reference; they are not claims about this product.

01
International Journal of Cosmetic Science · 2002
A synthetic hexapeptide (Argireline) with antiwrinkle activity
Blanes-Mira C, Clemente J, Jodas G, et al.
02
American Journal of Clinical Dermatology · 2013
The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study
Wang Y, Wang M, Xiao S, et al.

Studied alongside

SNAP-8
Acetyl octapeptide-3
from $32.00
Matrixyl
Palmitoyl pentapeptide-4
from $36.00

Research notice

Argireline is supplied for in vitro laboratory research and analytical use by qualified professionals. It is not a medicine, supplement or cosmetic, has not been evaluated by any regulator, and is not for human or veterinary use. Published findings cited on this page are provided for reference and are not claims about this product.