Growth Hormone Secretagogues

Sermorelin

GHRH(1–29) amide

Also known as GRF(1–29)-NH2, Geref.

The unmodified N-terminal 29-residue fragment of GHRH, the shortest sequence retaining full receptor activity, used as the reference GHRH analogue.

Current lot: SN-SER-2606
Purity: 99.11% by HPLC
Tested: Jun 14, 2026
Stocked in: United States, Canada

Synamino Sciences research vial with a silver cap on a navy background

Ships from

Vial size

$42.00

USD · 5 mg · In stock

Qty

Order by 2:00 PM PT for same-day dispatch from Reno, Nevada. 1–3 business days by USPS Priority and UPS. Free shipping over $150.00.

For laboratory research use only. Not for human or veterinary use.

About the compound

Sermorelin is the classic GHRH(1–29) fragment. Because it lacks stabilising substitutions, it is often used as the baseline against which modified analogues are compared.

Supplied as a lyophilized powder.

Studied inGHRH receptor · Analogue comparison · Pituitary cell models

Certificate of analysis

The certificate for the lot currently shipping. Every vial in that lot carries the same lot number on its label.

Certificate of analysis

Sermorelin · 5 mg

Lot SN-SER-2606 · tested Jun 14, 2026

99.11%

Purity by HPLC

Labeled: 5 mg
Measured: 5.1 mg
Panel: 6 passed · 2 reported
Laboratory: Independent ISO/IEC 17025 accredited laboratory

Assay	Method	Result	Outcome
Appearance	Visual	White lyophilized powder	Pass
Purity	HPLC · spec ≥ 98%	99.11%	Pass
Net peptide content	HPLC	5.1 mg	Reported
Identity	LC-MS	Confirmed	Pass
Heavy metals	ICP-MS	Not detected	Pass
Sterility	USP <71>	No growth	Pass
Endotoxin	LAL · USP <85>	< 0.05 EU/mL	Reported
Residual solvents	GC-HS	Within limits	Pass

Specification and storage

CAS number: 86168-78-7
Molecular formula: C149H246N44O42S
Molecular weight: 3357.9 g/mol
Residues: 29
Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Reference record: PubChem entry

Storage

Sealed lyophilized vials are stable at room temperature for short periods; store at 2–8 °C for routine use.
For long-term storage keep sealed vials at −20 °C, protected from light and moisture.
Reconstituted solutions should be refrigerated at 2–8 °C and used within the period defined by your laboratory's protocol.

Literature

Peer-reviewed publications on this compound. Provided for reference; they are not claims about this product.

01
BioDrugs · 1999
Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency
Prakash A, Goa KL
02
The Journal of Clinical Endocrinology & Metabolism · 1996
Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy
Thorner M, Rochiccioli P, Colle M, et al.
03
Biochemical and Biophysical Research Communications · 1983
In vivo biological potency of rat and human growth hormone-releasing factor and fragments of human growth hormone-releasing factor
Wehrenberg WB, Ling N

Studied alongside

CJC-1295 (No DAC)
Modified GRF 1–29
from $38.00
Ipamorelin
Pentapeptide GHS-R agonist
from $32.00

Research notice

Sermorelin is supplied for in vitro laboratory research and analytical use by qualified professionals. It is not a medicine, supplement or cosmetic, has not been evaluated by any regulator, and is not for human or veterinary use. Published findings cited on this page are provided for reference and are not claims about this product.